Stucki, D., Brites, D., Jeljeli, L., Coscolla, M., Liu, Q., Trauner, A., Fenner, L., Rutaihwa, L., Borrell, S., Luo, T., Gao, Q., Kato-Maeda, M., Ballif, M., Egger, M., Macedo, R., Mardassi, H., Moreno, M., Vilanova, G.T., Fyfe, J., Globan, M., Thomas, J., Jamieson, F., Guthrie, J.L., Asante-Poku, A., Yeboah-Manu, D., Wampande, E., Ssengooba, W., Joloba, M., Boom, W.H., Basu, I., Bower, J., Saraiva, M., Vasconcellos, S.E.G., Suffys, P., Koch, A., Wilkinson, R., Gail-Bekker, L., Malla, B., Ley, S.D., Beck, H.-P., De Jong, B.C., Toit, K., Sanchez-Padilla, E., Bonnet, M., Gil-Brusola, A., Frank, M., Penlap Beng, V.N., Eisenach, K., Alani, I., Ndung'U, P.W., Revathi, G., Gehre, F., Akter, S., Ntoumi, F., Stewart-Isherwood, L., Ntinginya, N.E., Rachow, A., Hoelscher, M., Cirillo, D.M., Skenders, G., Hoffner, S., Bakonyte, D., Stakenas, P., Diel, R., Crudu, V., Moldovan, O., Al-Hajoj, S., Otero, L., Barletta, F., Carter, E.J., Diero, L., Supply, P., Comas, I., Niemann, S., Gagneux, S. How does HIV infection influence the immune responses to Mycobacterium tuberculosis in the lung? What is the pathogenesis of tuberculous pericarditis? What is the cause and best management of the HIV-Tuberculosis-associated Immune Reconstitution Inflammatory Syndrome? This project is led by Professor Graeme Meintjes, Professor and Infectious Diseases Physician, CIDRI-Africa, UCT. How can tuberculosis infection in HIV infected people be more effectively prevented?īy what immune mechanisms do preventive therapies decrease susceptibility to TB? Projects underway at present include the following: Through clinically-based studies, they aim to improve knowledge of pathogenesis and thereby improve prevention and treatment. His research programme derives its research questions from the clinical care of tuberculosis (TB) and HIV-TB co-infected persons in South Africa and London. The epidemiology and clinical features of HIV associated TB are well researched, but few studies have addressed in detail the cellular mechanisms. HIV and TB are the most pressing public health problems in Africa: in South Africa, many hundreds of people still die prematurely per day because of HIV, many due to co-existent TB. Wilkinson’s interests are focused on clinical and immunological aspects of tuberculosis, particularly in the context of HIV-1 infection. Senior Group Leader at The Francis Crick Institute, London and Wellcome Senior Fellow in Clinical Science at Imperial College London Director, Centre for Infectious Diseases Research in Africa (CIDRI-Africa) Group leader and Director, Crick African Network and Member, Institute of Infectious Disease and Molecular Medicine Department of Medicine, Faculty of Health Sciences, University of Cape Town Splatwoon is probably one of the things that would make me really want to get a Switch when I think about it atm - as long as the weaknesses have been addressed.Selected publications | Contact details | Group members | Collaborations One of the things I loved about Splatoon actually was just seeing how the meta of it slowly changed over time! I'm a bit of a nerd for stuff like that though. It added some sort of new dimensions and freshness to the game when new weapons came out and the meta slowly changed. The slow trickle of content, whilst initially receiving mixed reactions, eventually wasn't too bad for me personally. i.e not being able to change loadouts without leaving lobbies, then waiting to get back into games(especially if trying to rejoin friends) and the 'rotation' of modes and limits of maps to 4 hourly intervals, the kick at the changeover time, balance for uneven teams etc. You have to consider though - that's 100 hours for me despite some noticeable flaws in the game. I recall one day when I think Moray Towers came out, me and were on for possibly half the day in and out lol - don't think any of us attended to the plans we actually had for the day! That was cool, though we were skyping at the same time which helped. Personally I ended up with at least 100 hours playtime out of the original. You should probably ask - I only dare wonder how many hours he's clocked up on this by now! Was the online addictive for you? As in time flies while playing it?
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